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Image Search Results
Journal: Journal of Radiation Research
Article Title: Comprehensive analysis for detecting radiation-specific molecules expressed during radiation-induced rat thyroid carcinogenesis
doi: 10.1093/jrr/rraa139
Figure Lengend Snippet: Quantitative analyses for expression levels of 12 genes as candidate biomarkers in irradiated thyroid gland using ddPCR. The y -axis represents the ratio of the expression level of each gene to β-actin expression. CDKN1A expression was significantly higher than that of the control at all time points and increased in a time-dependent manner.
Article Snippet: The sections were incubated for 1 h at 37°C with 1:50 dilution of anti-Ki-67 mouse monoclonal antibody (MIB-5, Dako) or 1:200 dilution of
Techniques: Expressing, Irradiation
Journal: Journal of Radiation Research
Article Title: Comprehensive analysis for detecting radiation-specific molecules expressed during radiation-induced rat thyroid carcinogenesis
doi: 10.1093/jrr/rraa139
Figure Lengend Snippet: Comparison of CDKN1A expression level in non-tumorous thyroid glands at 16 M between 4 Gy exposure and control groups in a randomized, controlled, double-blind study. Using 11.69 as the cut-off value for CDKN1A / β-actin for detecting irradiated thyroid glands, irradiated thyroid glands could be distinguished with high accuracy. The positive and negative predictive values were 100 and 69%, respectively.
Article Snippet: The sections were incubated for 1 h at 37°C with 1:50 dilution of anti-Ki-67 mouse monoclonal antibody (MIB-5, Dako) or 1:200 dilution of
Techniques: Expressing, Irradiation
Journal: Journal of Radiation Research
Article Title: Comprehensive analysis for detecting radiation-specific molecules expressed during radiation-induced rat thyroid carcinogenesis
doi: 10.1093/jrr/rraa139
Figure Lengend Snippet: Comparison of p21 immunoreactivity in non-tumorous thyroid tissues at 16 M between 4 Gy exposure and control groups. The level of p21 staining was scored as follows: negative, 0; faint nuclear staining, 1; moderate nuclear staining, 2; intense nuclear and cytoplasmic staining, 3. No statistical difference was observed between the two groups. P = 0.13 using the Mann–Whitney U test.
Article Snippet: The sections were incubated for 1 h at 37°C with 1:50 dilution of anti-Ki-67 mouse monoclonal antibody (MIB-5, Dako) or 1:200 dilution of
Techniques: Staining, MANN-WHITNEY